Tadalafil, Sildenafil, Vardenafil: What is the Difference?
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Tadalafil, Sildenafil, and Vardenafil are the main ingredients in the top three oral prescription treatments Generic Cialis, Generic Viagra, and Generic Levitra. All three are FDA-approved in the treatment of erectile dysfunction. Tadalafil, Sildenafil, and Vardenafil are all PDE5 inhibitors that work to expand the blood vessels in the penis to allow for an increased flow of blood to the region, thereby creating a hard, long lasting erection throughout sexual stimulation. All three drugs share common side effects, such as headache, nasal congestion, back pain, and facial flushing. Other side effects that all three drugs have in common are temporary vision changes, an elevation in blood pressure, and dizziness.
Men who want to take Tadalafil, Sildenafil, and Vardenafil to treat their erectile dysfunction should all discuss taking any of these medications with their doctor prior to buying them if they take medications such as alpha blockers and nitrates. These medications, when mixed, can cause a severe elevation in blood pressure. If a man wants to take both, it is advisable to wait 48 hours between medications. As well, men who suffer from certain medical conditions, including chest pains, a history of blood pressure issues, cardiovascular conditions, and kidney and liver disease, should also talk with their doctor and will have to be monitored while on the medication.
The question becomes where is the difference between Tadalafil, Sildenafil, and Vardenafil? All three work to help men who suffer from impotence, and if one medication does not work, another can be used instead (although take note that if one of the three erectile dysfunction medications do not work, then there is a likely possibility that the other medications will not work either).
The available dosage of all three does vary, though all three drugs, but they are most effective if taken about 30 to 60 minutes before sexual stimulation. Tadalafil, the main component in Cialis, is available in 5mg, 10mg, and 20mg pills, with most men starting on the 10mg dosage. Sildenafil is available in 25mg, 50mg, and 100mg tablets. Sildenafil, the first on the market with Viagra, has the best track record in helping men suffering from erectile dysfunction. Most doctors start their patients on 50mgs of Sildenafil and then either increases or decreases the dosage depending on your reaction to the medication. Vardenafil tablets come in 2.5mg, 5mg, 10mg, and 20mg doses. Most men begin with a 10mg dose for treatment of erectile dysfunction. Vardenafil is the fastest acting erectile dysfunction drug on the market – it only takes an average of 25 minutes for the tablet to do its magic.
But the main difference? The main difference lies in how long the pill lasts in the body before it metabolizes in the system. Both Sildenafil and Vardenafil last between four to six hours. However, Tadalafil can last in your system for 36 hours. This does not mean 36 hours a straight erection (any erection that lasts over four hours should go immediately to the hospital), what it does mean is that within 36 hours, if sexually stimulated, an erection will form. For this reason, Tadalafil is given the nickname the “weekend warrior” and is easier for men who don’t want to worry about taking a pill every day.
